Set in a post-atomic future where robotic Sentinels rule the United States many super powered beings have been hunted down and killed. The remaining mutants are incarcerated in concentration camps.

An older Kate Pryde has only one option to prevent this future, she transfers her mind into the younger, present-day Kitty Pryde.

Her aim is to convince the X-Men to help prevent a critical assassination which triggers anti-mutant hysteria.

If she fails, she will have to watch the X-Men die... again!

In X-Men: The Last Stand a chunk of the Days of Future Past reality is shown in the opening sequence of the motion picture. The Danger Room combat session used by Wolverine and Storm in which the battlefield is a devastated city, and their opponent is a Sentinel. In addition the whole bit When Wolverine tells Colossus to do a 'fast ball special' (i.e. throw) him at the Sentinel, Wolverine being hurled through the air into the Sentinel's 'death ray' and the screen whiteing out was lifted almost panel for panel out of this storyline.

In "Genesis" the first episode of NBC's television series Heroes, the character of Hiro Nakamura cites this storyline and Kitty's travelling through time as teaching him about the concepts of time travel.

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